Human respiratory syncytial virus (HRSV) is the major cause of lower respiratory tract infections in children under 5 years of age and the elderly, causing annual disease outbreaks during the fall and winter.Multiple lineages of the HRSVA and HRSVB serotypes co-circulate within a single outbreak and display a strongly temporal pattern of genetic va
Breast cancer, especially the aggressive triple-negative subtype, poses a serious health threat to women.Unfortunately, effective targets are lacking, leading to a grim prognosis.Research highlights the Toe Fillers crucial role of c-MYC overexpression in this form of cancer.Current inhibitors targeting c-MYC focus on stabilizing its G-quadruplex (G
ABSTRACT Objective: In this study, simulations were performed by the finite element method (FEM) to determine the tension and displacement Ring Holder in mini-implants and in expander appliance during rapid maxillary expansion, by varying the number and location of the mini-implants.Methods: For the computational simulation, a three-dimensional mes
Summary: Evolvability is an emergent hallmark of cancer that depends on intra-tumor heterogeneity and genetic variation.Mutations generated by APOBEC3 contribute to genetic variation and Television tumor evolvability.However, the influence of APOBEC3 on the evolvability of the genome and its differential impact on cancer genes versus non-cancer gen